Portfolio Companies

Current POrtfolio Companies

Ablative Solutions.jpg

High blood pressure, or hypertension, is both a disease and a risk factor for heart attack, stroke, heart failure and kidney disease. Ablative Solutions has developed a novel technology for treating hypertension. The Peregrine™ catheter system uses three micro-tubules and micro-needles to deliver alcohol as a neurolytic agent to denervate nerves outside of the renal artery which hormonally modulate blood pressure. As the only denervation company in the market using a chemical agent rather than radio frequency (RF) delivery, Ablative has a strong IP position within a billion-dollar industry. Human clinical data is strong, demonstrating superior and permanent results in lowering systolic blood pressure for drug-resistant hypertensives. ablativesolutions.com

eAgile.png

eAgile Inc. designs and manufacturers a comprehensive product line of wireless devices including; Auto-ID (Automatic Identification), RFID (Radio Frequency Identification, including UHF, HF/NFC and LF frequencies), RTLS (Real Time Location Systems) and supporting infrastructure. The company has established itself as a premier global supplier of RFID solutions with item-level tracking of assets in numerous high growth markets. Millions of eAgile tags are sold every year to a diverse client base deploying eAgile solutions in more than 40 countries across five continents. eagile.com

GRAM.jpg

After a partial exit of Grand River Aseptic Manufacturing (GRAM), GRAM Holdings was created for investors who wished to maintain investment in the company. GRAM was founded in 2010 as a joint venture between the Van Andel Institute and Grand Valley State University. The company supports the life sciences industry’s growing need for high-quality, outsourced sterile parenteral manufacturing. GRAM has more than 100 employees in two Grand Rapids locations with nearly 40,000 square feet of sophisticated cGMP space. The company provides customers with a full range of fill and finish needs, from early clinical fills through commercialization. grandriverasepticmfg.com

Intervention Insights.jpg

Intervention Insights provides actionable strategies that assist oncologists in developing personalized treatments for patients. The company analyzes cancerous tissue and generates a genomic picture of over 20,000 genes and molecular pathways that uniquely define a person’s cancer and the drugs that target them. This information is delivered to oncologists, who can quickly review hundreds of drugs which specifically target the molecular basis of a person’s cancer. interventioninsights.com

Metabolic Solutions.jpg

Metabolic Solutions Development Corporation (MSDC) is developing innovative therapeutics to treat diabetes and related symptoms of metabolic syndrome. This new approach seeks to improve treatment efficacy by freeing patients from adverse side effects such as edema and weight gain. msdrx.com

Rim Guard.png

Rim Guard Beet Juice Tire Ballast safely and cost-effectively maximizes pulling power, improves lifting performance, and reduces the risk of tipping. Based on a proprietary formulation that begins with a byproduct of sugar beet processing, Beet Juice is the heaviest non-corrosive tire ballast available and is cost-effective, non-toxic and safe for people, livestock and the environment. Since acquisition, the company has invested to upgrade equipment, improving operating efficiency and increasing profit margins. rimguardsolutions.com

SwiftBiosciences.png

Swift Biosciences develops and manufactures reagent kits for the rapidly growing areas of genetic and cancer research enabled by next-generation sequencing (NGS) technologies. Using extremely low DNA inputs, Swift is quickly becoming a market leader for DNA sample preparation. The tools developed in the company’s efforts are directly applicable to research in agrigenomics, biotechnology, metagenomics, and the pharmaceutical industry. swiftbiosci.com

Trice Medical was founded in December 2011 to focus on the problem of diagnosing joint injuries and the difficulties that exist in accurately identifying the source of pain and treating the underlying conditions. Trice has developed a proprietary device – the mi-eye 2™ – that combines a needle and camera and is used for internal visualization. This disposable device is used in a physician’s office as a diagnostic tool, eliminating the need, time delay, extraneous cost, and risk of false reads associated with an MRI scan. The company is currently in commercial sales. tricemedical.com

Vestaron.jpg

Vestaron is a leader in the development and marketing of safe and effective biological insecticides/miticides derived from naturally occurring peptides. The Spear® family of natural insecticides offers a new mode-of-action with no known resistance, with high efficacy when compared to existing less environmentally friendly insecticides. They are EPA-approved, classified as biological and designed to be non-toxic to fish, birds, humans and other mammals. Spear formulations are combined with proven Bacillus thuringiensis (Bt) natural insecticides for even greater effectiveness. vestaron.com

EXITED PORTFOLIO COMPANIES

Alliant.jpg

Alliant Healthcare Products (exited 2010) was established in 2002 to provide quality, cost-effective medical device products and services. With a core focus on the federal market, Alliant offers products and services from some of the most respected medical device manufacturers in the world, such as Philips, Olympus, Skytron, Belimed, Enovate, and many more. A vast array of contracting tools allow the government to purchase products through Alliant easily, efficiently, and inexpensively. allianthealthcare.com

GRAM.jpg

Grand River Aseptic Manufacturing (partial exit 2017) was founded in 2010 as a joint venture between the Van Andel Institute and Grand Valley State University. The company supports the life sciences industry’s growing need for high-quality, outsourced sterile parenteral manufacturing. GRAM has more than 100 employees in two Grand Rapids locations with nearly 40,000 square feet of sophisticated cGMP space. The company provides customers with a full range of fill and finish needs, from early clinical fills through commercialization. grandriverasepticmfg.com

nanoRETE (exited 2016) was formed to replace current, suboptimal tuberculosis screening tests with a superior diagnostic tool advancing the market to single point of care. Early pre-clinical trial results demonstrated comparable sensitivity and superior selectivity against the market standard with a greater than 80% reduction in test time, translating to significant savings in laboratory labor burden.

RespondWell.png

RespondWell (exited 2016) developed a proprietary software package that facilitates, manages, and reports patients’ rehabilitation using 3D sensor technology found in the Xbox Kinect. With the RespondWell system, patients utilize various condition-specific modules through gamified sessions that record and report patient results to providers and payors. The positive rewards and game-like scenarios encourage patients to continue rehab longer, producing better outcomes. The award-winning telerehabilitation technology was acquired by Zimmer Biomet Holdings, a global leader in musculoskeletal healthcare. zbmymobility.com

TRS.jpg

Tissue Regeneration Systems (exited 2014) is a start-up medical device company commercializing a breakthrough skeletal reconstruction and bone regeneration technology platform licensed from the Universities of Michigan and Wisconsin. The technology has been evaluated in several large animal studies with very promising long-term results. The company has completed all required bench and animal testing and received 510K approval from the FDA, clearing both the technology platform and its first product for commercialization in the United States. The company recently established a fully integrated, FDA-compliant manufacturing operation. To learn more about the collaboration between TRS and Johnson & Johnson, visit https://www.jnj.com/innovation/trs for an informative 5-minute video. tissuesys.com

TransCorp Spine.png

TransCorp Spine (exited 2016) offers products and procedures for treatment of herniated cervical disks that are less invasive than traditional methods, enabling patients to recover more quickly. TransCorp Spine products enable the surgeon to rapidly, safely, and effectively decompress the cervical spine without the need to perform a diskectomy, fusion or arthroplasty. transcorpspine.com

ADDITIONAL